Medical Support and Findings of the Skylab Program

Specific equipment used in carrying out Skylab medical experiments is outlined and illustrated. Also included are reviews of the techniques, frequency, and protocols of the tests designed to study the long term effects of weightlessness on the human body. In-flight investigations were an evaluation of the cardiovascular system, a study of metabolic activity, investigations in the field of neurophysiology, the determination of changes in body fluids, a precise measurement of total body metabolism, and a study of crew performance by use of a time and motion experiment. Significant data obtained from in-flight and postflight tests are outlined

Space Biology and Medicine

Volume IV is devoted to examining the medical and associated organizational measures used to maintain the health of space crews and to support their performance before, during, and after space flight. These measures, collectively known as the medical flight support system, are important contributors to the safety and success of space flight. The contributions of space hardware and the spacecraft environment to flight safety and mission success are covered in previous volumes of the Space Biology and Medicine series. In Volume IV, we address means of improving the reliability of people who are required to function in the unfamiliar environment of space flight as well as the importance of those who support the crew. Please note that the extensive collaboration between Russian and American teams for this volume of work resulted in a timeframe of publication longer than originally anticipated. Therefore, new research or insights may have emerged since the authors composed their chapters and references. This volume includes a list of authors' names and addresses should readers seek specifics on new information. At least three groups of factors act to perturb human physiological homeostasis during space flight. All have significant influence on health, psychological, and emotional status, tolerance, and work capacity. The first and most important of these factors is weightlessness, the most specific and radical change in the ambient environment; it causes a variety of functional and structural changes in human physiology. The second group of factors precludes the constraints associated with living in the sealed, confined environment of spacecraft. Although these factors are not unique to space flight, the limitations they entail in terms of an uncomfortable environment can diminish the well-being and performance of crewmembers in space. The third group of factors includes the occupational and social factors associated with the difficult, critical nature of the crewmembers' work: the risks involved in space flight, changes in circadian rhythms, and intragroup interactions. The physical and emotional stress and fatigue that develop under these conditions also can disturb human health and performance. In addition to these factors, the risk also exists that crewmembers will develop various illnesses during flight. The risk of illness is no less during space flight than on Earth, and may actually be greater for some classes of diseases

Experiment M-3: In-Flight Exerciser

The response of the cardiovascular system to a quantified workload is an index of the general physical condition of an individual. Utilizing mild exercise as a provocative stimulus, no significant decrement in the physical condition of either of the two astronauts could be detected during the Gemini V mission. The rate of return of the pulse rate to pre-exercise levels, following in-flight exercise periods, was essentially the same as that observed during preflight baseline studies

Experiment M-1: Cardiovascular Conditioning

Intermittent venous occlusion of the extremities of man, during weightlessness simulation studies, has been demonstrated to be effective in preventing or mitigating the orthostatic hypotension observed following such simulations. A similar preventive measure was employed on the pilot of Gemini V with a view to determining the efficacy of pulsatile leg cuffs in preventing or lessening the orthostatic hypotension observed following previous space flights. Unfortunately, the cuff device was operative continuously during only the first 4 days of the 8-day mission. Post flight tilt-table responses of the command pilot and the pilot were considerably different, but the data cannot be construed as a conclusive demonstration that the observed differences were the result of the action of the pulsatile cuffs. The differences in the tilt responses of the Gemini V flight crew may be only a reflection of individual variability so commonly observed in biological experimentation. More data shall be required before a judgement can be rendered as to the efficacy of the pulsatile-leg-cuff technique in lessening postflight postural or orthostatic hypotension